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The team specifically targeted the parasites mitochondrial kinetoplast DNA (kDNA) and nuclear satellite DNA (SAT) regions using nested and quantitative PCR (qPCR)

1 AUC values shown in this table were calculated directly from each participants concentration-time data using noncompartmental methods, and therefore differ from the model-based estimated mean AUCs reported elsewhere in the manuscript, which were obtained from linear mixed-effects models fitted on log-transformed AUC and back-transformed to the original scale (estimated marginal means)

For most small GTPases, including Ran, the water molecule is positioned by interaction with a conserved glutamine residue (Gln61 in Ras, Gln69 in Ran), immediately following the DxxG motif in the switch II region of the small GTPase

Peripheral Neuropathy Fact Sheet , (2016)

GHK-Cu Mechanism of Action GHK-Cu peptide functions by interacting with cells to promote skin health and repair through several mechanisms

Glutamate: a neurotransmitter in mammalian brain